Maximizing Glute Growth. The Glutes are made up of four main muscles, the Gluteus Maximus, Medius, Minimus, and the Piriformis. Each plays a key role in movement. Gluteus Maximus: This is the biggest muscle and the one most people think of when they think “glutes”. It’s also the muscle that provides most of the front-to-back and overall size of the glutes. It performs many functions, but is perfect for hip extension. Thus, exercises like the back squat, sumo deadlift, RDL,